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CRISPR Genome Editing Lead Researcher (Tsai Lab)

Company: St. Jude Children's Research Hospital
Location: Memphis
Posted on: June 25, 2022

Job Description:

The Tsai lab is a collaborative, creative and fun academic lab group at St. Jude Children's Research Hospital focused on advancing genome editing technologies for therapeutics. We are known for developing state-of-the-art genomic methods to understand and improve genome editors, and translating them for therapeutic applications. Dr. Tsai was chosen as one of the American Society for Gene and Cell Therapy (ASGCT) Outstanding New Investigators in 2020 and is one of the co-chairs of the Steering Committee of the NIH Somatic Cell Genome Editing Consortium.
We are seeking an outstanding, experienced, and highly-motivated Lead Researcher to help us advance state-of-the-art genome editing approaches for Cas12a nucleases. We care deeply about the success of our scientists and this is a unique opportunity to work on understanding a class of novel CRISPR genome editors.
You will work in a highly collaborative and fast-paced team focused on developing state-of-the art approaches to understand the genome-wide off-target activity of genome editors. As a Lead Researcher you will use high-throughput genomic approaches to characterize the safety of Cas12a genome editors, and help generate key data to support the development of novel engineered versions of Cas12a.
Application processApply now to join our talented team! Please include your CV and a cover letter addressed to Dr. Tsai who will read and review all qualified applications.


  • Genomic studies to understand the safety of genome editors, primarily Cas12a variants.
    • Analyze experimental outcomes and develop high-quality summaries towards manuscripts and grant applications.
    • Draft manuscripts and figures for publication in high-impact journals.

      • Bachelor's degree in relevant scientific area is required

        • Five (5) years of relevant, post-degree work experience is required
        • Two (2) years of relevant post-degree work experience is required with a Master's degree
        • No experience is required with a PHD
        • Master or Ph.D. in a relevant field, such as molecular and cell biology, genetics, or genomics preferred
        • Experienced with molecular cloning, mammalian cell culture and mammalian cell transfection preferred
        • Excellent communication, organizational, and presentation skills preferred
          St. Jude Children's Research Hospital is one of the world's leading pediatric hospitals whose mission is to advances cures for catastrophic childhood diseases. Consistent with the vision of our founder, no child is denied treatment based on race, religion, or ability to pay.
          St. Jude has been consistently named one of the best companies to work for by Fortune, GlassDoor, and others. St. Jude offers excellent benefits, great salary, help with relocation, and actively fosters professional development. As part of your role, you will have opportunities to attend and present at national and international meetings such as ASGCT, ASH, Keystone Genome Engineering, CSHL Genome Editing, and FASEB Genome Engineering.
          COVID-19 vaccine:
          As of September 10, 2021, St. Jude Children's Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.
          EEO Statement: St. Jude is an Equal Opportunity EmployerNo Search Firms:St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Keywords: St. Jude Children's Research Hospital, Memphis , CRISPR Genome Editing Lead Researcher (Tsai Lab), Advertising , Memphis, Tennessee

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