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CRISPR-Cas Genome Editing Research Technologist (Hematology)

Company: St. Jude Children's Research Hospital
Location: Memphis
Posted on: April 16, 2019

Job Description:

OverviewThe laboratories of Shengdar Q. Tsai and Yong Cheng are seeking outstanding, highly motivated, and creative candidates for a Research Technologist to define and improve genome editing strategies for treatment of sickle cell disease and cancer immunotherapy.

You will have the opportunity to learn about and support new exciting projects such as:



  • Perform functional epigenomic profiling such as ChIP-seq, ATAC-seq, RNA-seq, Hi-C to understand the organization of chromatin and its relationship to genome editing
  • Develop new genomic methods and single-cell based approaches to understand the global biological effects of genome editing
  • Perform functional epigenomic profiling to define the relationship between genome-wide editing activity in vitro and in cells
  • Optimizing pre-clinical CRISPR-Cas gene editing strategies for induction of fetal hemoglobin as a therapeutic replacement for sickle adult hemoglobin

    In this position, you will gain extensive experience and training in epigenomics, gene editing, protein engineering, different high-throughput and single-cell sequencing-based technologies.

    Learn more by clicking here.Minimum EducationBachelor's or Master's degree in an appropriate scientific field is required.Minimum ExperienceSuccessful applicants will have excellent communication skills, and a B.S. or equivalent degree in molecular biology, cell biology, genetics, genomics, hematology, or a related area is required. To succeed in this position, you will have a strong molecular and cell biology background, with an emphasis on molecular cloning and genetic manipulation of mammalian cells. Applicants with experience in any of the following are strongly encouraged to apply: human hematopoietic stem cells, human T-cells, genome editing, genomics, next-generation sequencing, or automated liquid handling.Other Credentials

    EEO StatementSt. Jude is an Equal Opportunity EmployerNo Search Firms:St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Keywords: St. Jude Children's Research Hospital, Memphis , CRISPR-Cas Genome Editing Research Technologist (Hematology), Advertising , Memphis, Tennessee

Click here to apply!

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